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Pulling a scoop of casserole out of the skillet
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4.73 from 18 votes

Meatball Sub Casserole

All the flavors of a great meatball sub are combined in this easy casserole!
Prep Time5 mins
Cook Time45 mins
Total Time50 mins
Course: Entree, Main Course
Cuisine: Italian
Keyword: meatball casserole, meatball sub, pantry meal
Servings: 6 servings
Calories: 549kcal
Author: The Chunky Chef


  • 1 can 8 count refrigerated biscuits
  • 14 oz bag Frozen Italian Style Meatballs, thawed (I use the 1/2 oz size meatball, which has about 28 meatballs in the bag)
  • 1 1/2 cups marinara sauce
  • 1/2 tsp garlic powder
  • 1/2 tsp Italian seasoning
  • 2 cups shredded mozzarella cheese
  • fresh basil or parsley, minced (optional - for garnish)


  • Preheat oven to 375 F degrees and spray a large oven safe skillet or 3 qt baking dish with non stick spray.  Set aside.  Lightly spray one side of a piece of aluminum foil with non stick spray and set aside.
  • Remove biscuit dough from can and slice each biscuit into 8 pieces.  Add to greased skillet or baking dish.
  • Top with marinara sauce, garlic powder and Italian seasoning.  Stir around to mix seasonings into sauce and coat dough in sauce.
  • Nestle thawed meatballs into and on top of the dough pieces.  Cover with half the shredded cheese, and cover skillet or dish with foil, sprayed side down.
  • Bake for 30 minutes, remove foil, add remaining cheese, and bake another 15 minutes until bubbly and cheese is melted.  If desired, broil a minute or two.
  • Serve hot, garnished with fresh herbs, if using.


If you have trouble with your dough not cooking all the way through, you could also heat the sauce and thawed meatballs until bubbly and hot, THEN add them to the biscuit dough and toss it all together, cover and bake.


Calories: 549kcal